منابع مشابه
Effect of polypharmacy, potentially inappropriate medications and anticholinergic burden on clinical outcomes: a retrospective cohort study.
BACKGROUND Polypharmacy, potentially inappropriate medications and anticholinergic burden (as assessed by the anticholinergic risk scale) are commonly used as quality indicators of pharmacotherapy in older adults. However, their role in clinical practice is undefined. We sought to investigate longitudinal changes in these indicators and their effects on clinical outcomes. METHODS We used Taiw...
متن کاملPolypharmacy and adverse outcomes after hip fracture surgery
BACKGROUND We aimed to explore the effects of polypharmacy and specific drug classes on readmissions and mortality after hip surgery. METHODS We analyzed data on 272 consecutive hip fracture patients (72.1% females; age 82 ± 9 years) who underwent acute hip replacement. We collected detailed data on the pharmacological treatment upon admission and discharge. Patients were followed up over a p...
متن کاملClinical Outcomes of Intramedullary and Extramedullary Fixation in Unstable Intertrochanteric Fractures: A Randomized Clinical Trial
Background: The best method for repairing intertrochanteric fractures is still controversial. The fixation methods includeextramedullary (EM) and intramedullary (IM). Studies that compare IM and EM fixations for unstable hip fractures arerare. In this study, our goal was to compare the efficacy of EM and IM fixation in treatment of unstable intertrochantericfractures.Met...
متن کاملThe Epidemiologic and Clinical Study on Hemiscorpius Lepturus (Gadim) Envenomation with Focus on Clinical Manifestations, Prognosis Factors, and Outcomes
Background: Hemiscorpius lepturus envenomation is one of the most important medical issues in tropical regions of Iran, especially Khuzestan Province. Due to lack of reliable data about scorpion sting in Khuzestan Province, this investigation was performed to study the clinical presentation, prognosis factors, complications and mortality rates of Hemiscorpius lepturus sting. Methods: this study...
متن کاملRational polypharmacy
The development of assays for plasma antiepileptic drug concentrations has led to the discovery of many pharmacokinetic interactions, some causing drug intoxication and others resulting in ineffective drug concentrations. In the 1970s, a number of epileptologists began to argue that single drug therapy was desirable in the treatment of epilepsy and this has become the accepted policy when initi...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2015
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.1150049